Trimethylglycine, or betaine HCl, is a cofactor for an enzyme that converts homocysteine back into methionine.1 Homocysteine “affects collagen by interfering with the cross-linking between the collagen fibers and the tissues they reinforce.”2 Collagen is one of the components of cartilage.
1https://en.wikipedia.org/wiki/Trimethylglycine
2https://www.ncbi.nlm.nih.gov/pubmed/16531613
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